منابع مشابه
Methylation matters.
DNA methylation is not just for basic scientists any more. There is a growing awareness in the medical field that having the correct pattern of genomic methylation is essential for healthy cells and organs. If methylation patterns are not properly established or maintained, disorders as diverse as mental retardation, immune deficiency, and sporadic or inherited cancers may follow. Through inapp...
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Transcription control was once an understandable topic. The prevailing view was that transcription factors sought out and bound to specific DNA sequences, thereby introducing activators or repressors to particular target genes. Although these interactions could erect elaborate castles on DNA, it was possible to consider these edifices as a kind of simplistic “Lego model.” For more than a decade...
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Child development might be conceptualized as experiences becoming sculpted in the organism’s DNA through methylation, one of the major epigenetic mechanisms of change. This article introduces some of the basic biological mechanisms of methylation, discusses research on animal models, and highlights some of the most impressive methylation studies on human development. Although assessment of meth...
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Epigenetic modifications are heritable changes in gene expression without changes in DNA sequence. DNA methylation has been implicated in the control of several cellular processes including differentiation, gene regulation, development, genomic imprinting and X-chromosome inactivation. Methylated cytosine residues at CpG dinucleotides are commonly associated with gene repression; conversely, st...
متن کامل($phi,rho$)-Representation of $Gamma$-So-Rings
A $Gamma$-so-ring is a structure possessing a natural partial ordering, an infinitary partial addition and a ternary multiplication, subject to a set of axioms. The partial functions under disjoint-domain sums and functional composition is a $Gamma$-so-ring. In this paper we introduce the notions of subdirect product and $(phi,rho)$-product of $Gamma$-so-rings and study $(phi,rho)$-represen...
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ژورنال
عنوان ژورنال: Cell Adhesion & Migration
سال: 2011
ISSN: 1933-6918,1933-6926
DOI: 10.4161/cam.5.1.13196